INDUSTRY LEADER IN CARDIOPULMONARY DIAGNOSTIC SERVICES

We offer individual-specific management feedback with data-driven state of the art technology using powerful proprietary pattern recognition software derived from testing over 230,000 patients in the healthcare system. Implementing our 20 years of real-world expertise working with doctors enables at-risk organizations to reduce healthcare costs by optimizing the cardiovascular health of their population.

15.5 Million

People diagnosed in the U.S. 1

370,000

Deaths in the U.S. per year 2

$182 Billion

U.S. cost per year 1

1.  American Heart Association, 2015 Heart Disease and Stroke Statistics Update.

2. Centers for Disease Control and Prevention, Heart Disease Facts.

Scientific Reports

The Complementary Role of Cardiopulmonary Exercise Testing   in Coronary Artery Disease: From Early Diagnosis to Tailored Management


Coronary artery disease (CAD) remains a leading cause of morbidity and mortality worldwide, accounting for over 9 million deaths annually. The prevalence of CAD continues to rise, driven by ageing and the increasing prevalence of risk factors such as hypertension, diabetes, and obesity. Current clinical guidelines emphasize the importance of functional tests in the diagnostic pathway, particularly for assessing the presence and severity of ischemia. While recommended tests are valuable, they may not fully capture the complex physiological responses to exercise or provide the necessary detail to tailor personalized treatment plans. Cardiopulmonary exercise testing (CPET) offers a comprehensive assessment of the cardiovascular, pulmonary, and muscular systems under stress, potentially addressing these gaps and providing a more precise understanding of CAD, particularly in settings where traditional diagnostics may be insufficient. By enabling more personalized and precise treatment strategies, CPET could play a central role in the future of CAD management. This narrative review examines the current evidence supporting the use of CPET in CAD diagnosis and management and explores the potential for integrating CPET into existing clinical guidelines, considering its diagnostic and prognostic capabilities, cost-effectiveness, and the challenges associated with its adoption.


Correlation between coronary microvascular dysfunction and cardiorespiratory fitness in patients with ST-segment elevation myocardial infarction


An 𝗲𝘅𝗰𝗶𝘁𝗶𝗻𝗴 𝗹𝗮𝗻𝗱𝗺𝗮𝗿𝗸 𝘀𝘁𝘂𝗱𝘆 just published in the highly prestigious journal 𝗡𝗮𝘁𝘂𝗿𝗲 demonstrates for the  first time a direct link between microvascular heart disease and cardiac dysfunction detected by cardiopulmonary exercise testing (𝗖𝗣𝗘𝗧). This has enormous implications for heart disease prevention as well as women's heart disease. CPET is the only modality that offers a safe, non-invasive and effective way to detect subclinical heart disease in patients without “blocked arteries”. Women with symptoms typically have normal routine testing in cardiology offices and can now get a definitive diagnosis and treatment plan. Asymptomatic individuals can use the information to develop customized exercise prescriptions with our without medical therapy. Everyone can closely follow their progress and make adjustments accordingly to optimize their long-term health.


Cardiopulmonary exercise testing and efficacy of percutaneous coronary intervention: a substudy of the ORBITA trial


Only a select group of CAD patients undergoing coronary stent procedures actually experience an improvement in angina and quality of life. Out of the non-invasive and invasive tools available,  CPET is currently the most effective at determining which patients are likely to benefit from coronary stent placements and which patients are likely to see no significant changes post-op.


The evolving role of cardiopulmonary exercise testing in ischemic heart disease – state of the art review


September 08, 2023 - Cardiopulmonary exercise testing (CPET) is the  gold standard for directly assessing cardiorespiratory fitness (CRF) and has a relatively new and evolving role in evaluating atherosclerotic heart disease, particularly in detecting cardiac dysfunction caused by ischemic heart disease. The purpose of this review is to assess the current literature on the link between cardiovascular (CV) risk factors, cardiac dysfunction and CRF assessed by CPET.

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WHAT IS CARDIOPULMONARY EXERCISE TEST (CPET)?

Cardiopulmonary Exercise Test (CPET) is the only non-invasive exercise stress test that assesses heart and lung function in real-time during exercise. Your heart and lungs work together to deliver oxygen to your working muscles where it is used to make energy; and to remove carbon dioxide from the body. CPET measures the amount of oxygen your body is using, the amount of carbon dioxide it is producing, your breathing pattern, and electrocardiogram (EKG) while you are riding a stationary bicycle.  


This data undergoes expert analysis in the data center where exercise capacity is quantified using MET-TEST powerful proprietary pattern recognition software, and the mechanism of patient symptoms is prioritized.


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WHAT IS PEAK VO2 AND WHY IS IT SO IMPORTANT?

Cardiorespiratory Fitness, also known as Functional Capacity or Exercise Capacity is the #1 predictor of longevity and all-cause mortality . Fitness is quantified as the volume of oxygen metabolized at peak exercise in ml/kg/min and is expressed as VO2-Max (Maximal Muscle Aerobic Capacity) or Peak VO2 (Highest level of O2 consumption attained at peak exercise). Low levels of fitness (Peak VO2) have been linked to decreased survival from heart disease, stroke, lung disease, cancer, kidney disease as well as increased incidence of hypertension, diabetes, high cholesterol, dementia, pneumonia and osteoporosis (weak bones). Peak VO2 is an accurate reflection of chronic diseases on the aging process and reflects the physiological “reserve” remaining in an individual. Based on age, height, weight and sex, each person has Peak VO2 values that correspond to 100% of predicted. Individuals with Peak VO2 > 100% predicted live the longest with fewest health problems whereas those with Peak VO2 < 60% of predicted have the shortest survival with the most health problems in a dose-dependent manner. Healthcare costs have also been shown to increase incrementally with decreasing peak VO2.

“Individuals whose Peak VO2 increases between examinations have a lower risk of adverse health and clinical outcomes than those whose Peak VO2 decreases, and this should be communicated to patients”. 1

Thus, the goal in every person is to increase Peak VO2 from baseline to provide objective evidence that long-term survival and healthcare costs are headed in the right direction. Increasing functional capacity (Peak VO2 ) requires an intricate understanding of the mechanism of exercise limitation (the cause of symptoms in patients with shortness of breath, chest pain and fatigue). Therapeutic interventions must target the primary mechanism of exercise limitation in order to increase Peak VO2. MET-TEST has 20 years of real-world expertise in assisting primary doctors and cardiologists to more precisely identify the cause of exercise limitation and target therapy accordingly.

 1. Ross et al.  Importance of Assessing Cardiorespiratory Fitness in Clinical Practice: A Case for Fitness as a Clinical Vital Sign: A

    Scientific Statement From the American Heart Association.  Circulation. 2016;134:00–00.

2. JACC Journals: (Mayo clin Proc 2018:93(1):48-55)

FIREFIGHTERS AND FIRST RESPONDERS

Sudden cardiac death accounts for approximately half of all on-duty death among firefighters

Firefighting work demands can be extreme and an accurate assessment of cardiopulmonary status, as well as detection and treatment of any underlying cardiovascular disease, is critical to ensured firefighter fitness for duty and prevent on-duty cardiac events or death. Exercise stress testing serves two primary purposes in assessing firefighter safety; evaluation of cardiorespiratory fitness and detection of under-treated cardiovascular disease. Cardiopumonary Exercise Testing (CPET) has made significant advances in the last decade and is superior to the traditional Treadmill stress test (Treadmill vs. CPET). To accomplish these goals upgrade to MET-TEST. 


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Firefighter Safety Thru Advanced Research (FSTR) Recommends CPET over Traditional Stress Testing.

Featured Study - Published: 2010 by The Journal of Strength and Conditioning Research 

UPGRADE YOUR ANNUAL TREADMIL TEST TO MET-TEST

In order to provide first responders with more concrete information about their health, MET-TEST developed a three-step program that offers measurable, actionable health data.

WOMEN'S HEALTH AND CPET

Over the last decade, our understanding of women’s heart disease has improved exponentially, and it has become apparent that heart disease affects men and women in different ways. Here are some facts about heart disease in women: (1,2,3)

 

  • Heart disease is the number #1 cause of death in women
  • 1 in 3 women will die of a heart attack or stroke
  • Heart disease causes more deaths in women than all forms of cancer combined
  • Two-thirds of women with heart disease report no symptoms prior to a heart attack
  • Almost half of African-American women over the age of 20 have heart disease
  • 90% of all women have 1 or more risk factors for heart disease and stroke

 

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